Human gene and microbial analyses in rectal cancer complete responses to radiotherapy.

Arielle Kae Sulit Kasmira WilsonJohn PearsonOlin K SilanderShienny SampurnoMichael MichaelRobert George Ramsay Alexander G HeriotFrank FrizelleRachel Violet Purcell

Published in: BJS open (2023)

These results identify potential genetic and microbial biomarkers of response to chemoradiotherapy in rectal cancer, as well as suggesting a potential mechanism of complete response to chemoradiotherapy that may benefit further testing in the laboratory.

Keyphrases

rectal cancer
locally advanced
microbial community
genome wide
endothelial cells
squamous cell carcinoma
copy number
radiation therapy
early stage
human health
gene expression
transcription factor
induced pluripotent stem cells