Impact of cyclosporine A concentration on acute graft-vs-host disease incidence after haploidentical hematopoietic cell transplantation.

Nicolas StockerRemy DuléryGiorgia BattipagliaEolia BrissotClémence MédiavillaSimona SestiliAnnalisa PaviglianitiTounes LedraaRazan MohtyAbdulhamid BazarbachiRamdane BelhocineAnne VekhoffAnnalisa RuggeriFlorent Malard Florent Malard

Published in: European journal of haematology (2019)

CsA could be initiated early before Haplo-HCT with achievement of high CsA concentration to reduce the risk of aGvHD without any detrimental effect on relapse.

Keyphrases

liver failure
stem cell transplantation
risk factors
bone marrow
respiratory failure
peripheral blood
drug induced
free survival
cell cycle arrest
cell proliferation
cell death
pi k akt