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Checkmate 77T: Perioperative chemoimmunotherapy outperforms in early-stage NSCLC.

Danielle BrazelMisako Nagasaka
Published in: Med (New York, N.Y.) (2024)
Approximately 1 in 4 patients with NSCLC present with resectable disease. Although surgery is potentially curative, 30%-50% of patients relapse. Studies have shown that neoadjuvant, adjuvant, and perioperative chemoimmunotherapy improve outcomes. The Checkmate 77T trial explored if perioperative platinum-based chemotherapy plus nivolumab, surgical resection, then adjuvant nivolumab further improved outcomes including EFS. 1 .
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