Total Flavonoids of Rhizoma Drynariae Treat Osteoarthritis by Inhibiting Arachidonic Acid Metabolites Through AMPK/NFκB Pathway.

Guang-Yao Chen Xiao-Yu Liu Xue-Er Yan Xin-Bo YuYi LiuJing LuoQing-Wen Tao

Published in: Journal of inflammation research (2023)

TFRD can inhibit COX-2-mediated arachidonic acid metabolites, and its mechanism is closely related to AMPK/NFκB pathway, which may be a key mechanism in the treatment of OA.

Keyphrases

signaling pathway
ms ms
lps induced
pi k akt
skeletal muscle
nuclear factor
knee osteoarthritis
oxidative stress
rheumatoid arthritis
protein kinase
inflammatory response
cell proliferation
immune response
toll like receptor