Effects of Optic Neuritis, T2 Lesions, and Microstructural Diffusion Integrity in the Visual Pathway on Cortical Thickness in Pediatric-Onset Multiple Sclerosis.
Ritobrato DattaJohn R SolleeAmy M LaveryGabriella Ficerai-GarlandKrystle KaroscikGeraldine LiuBrenda L BanwellAmy T WaldmanPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2019)
POMS negatively impacts the integrity of the anterior visual pathway, but it is the loss of WM integrity that drives anterograde loss of the cortical mantle. Preserved visual acuity and foveal sparing imply some degree of functional and structural resilience.