Comprehensive evaluation of patterns of hypoglycemia unawareness (HUA) and glycemic variability (GV) in patients with fibrocalculous pancreatic diabetes (FCPD): A cross-sectional study from South India.

Riddhi DasguptaFelix K JebasinghShajith AnoopSanthya SeenivasanMathews Edatharayil KurianFlory ChristinaGracy VarghesePamela ChristudossK U LijeshDeepu DavidSudipta Dhar ChowdhuryThomas V PaulNihal Thomas

Published in: PloS one (2022)

Heterogeneity in patterns of glucagon secretion were significantly associated with HUA and GV. Reduced glucagon levels contribute to greater risks of HUA, nocturnal hypoglycemia and greater GV, while hyperglucagonemia predisposes to postprandial hyperglycemia and hypoglycemia awareness in patients with FCPD.

Keyphrases

type diabetes
glycemic control
blood glucose
cardiovascular disease
insulin resistance
blood pressure
obstructive sleep apnea
physical activity
single cell
human health
risk factors
climate change
metabolic syndrome
skeletal muscle
diabetic rats