Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation.
Maryam OroujeniMatilda CarlqvistEva RyerAnna OrlovaVladimir TolmachevFredrik Y FrejdPublished in: EJNMMI radiopharmacy and chemistry (2024)
The improved functional affinity by dimerization does not compensate the disadvantage of increased molecular size for imaging purposes.
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