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Visible-light-mediated C-H amidation of imidazoheterocycles with N -amidopyridiniums.

Lili WenQiannan TanChao PiJuan YuanJingyu ZhangXia Mi
Published in: Organic & biomolecular chemistry (2024)
C-3 amidated imidazoheterocycles were synthesized via a visible light-promoted reaction of imidazoheterocycles with N -amidopyridinium salts catalyzed by 4CzIPN under mild conditions. For imidazoheterocycles and N -amidopyridinium salts with various substituents, the reaction proceeded smoothly to give the corresponding products in moderate to good yields. The reaction provides a new strategy for the synthesis of secondary amides with the imidazo[1,2- a ]pyridine core.
Keyphrases
  • visible light
  • ionic liquid
  • high intensity