A strong association between VEGF-A rs28357093 and amyotrophic lateral sclerosis: a brazilian genetic study.

Caroline Christine Pincela da CostaNayane Soares de LimaDhiogo da Cruz Pereira BentoRodrigo da Silva Santos Angela Adamski da Silva Reis

Published in: Molecular biology reports (2022)

The mutant allele was more frequent in ALS patients (p < 0.001) and this finding could be associated with ALS risk. This first study from the Brazilian central population was conducted to provide new insight into the pathogenesis of ALS.

Keyphrases

amyotrophic lateral sclerosis
end stage renal disease
chronic kidney disease
newly diagnosed
endothelial cells
dna methylation
patient reported outcomes