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Visual outcomes after anterior temporal lobectomy and transsylvian selective amygdalohippocampectomy: A quantitative comparison of clinical and diffusion data.

Philip PrucknerKarl-Heinz NenningFlorian Ph S FischmeisterMehmet-Salih YildirimMichelle SchwarzAndreas ReitnerSusanne Aull-WatschingerJohannes KorenChristoph BaumgartnerDaniela PrayerKarl RösslerChristian DorferThomas CzechEkaterina PataraiaGregor KasprianSilvia Bonelli
Published in: Epilepsia (2023)
In the context of controversial visual outcomes following epilepsy surgery, this study provides clinical as well as neuroimaging evidence for a higher risk and greater severity of postoperative VFDs after ATL compared to tsSAHE. Volumetric OpR tractography damage is a feasible parameter to reliably predict this morbidity in both treatment groups and may ultimately support personalized planning of surgical candidates. Advanced diffusion analysis tools such as FBA offer a structural explanation of surgically induced visual pathway damage, allowing noninvasive quantification and visualization of micro- and macrostructural tract affection.
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