Sensitivity and specificity of phrenic nerve electrophysiology to predict mechanical ventilation in the Guillain-Barré syndrome.
Kancha NareshAnupama RoyShreya SrivastavaPaul PremkumarAditya NairArun Mathai ManiAtif ShaikhPrabhakar Appaswamy ThirumalAjith SivadasanVivek MathewPrasanna Samuel PremkumarRohit Ninan BenjaminPublished in: Muscle & nerve (2023)
Our study suggests that phrenic CMAP amplitudes can predict the need for mechanical ventilation in GBS. In contrast, phrenic CMAP latencies are not reliable. The high negative predictive value of phrenic CMAP amplitudes ≥0.6 mV can preclude mechanical ventilation, making these a useful adjunct to clinical decision-making.