Leveraging the increased rates of pathologic complete response after neoadjuvant treatment in breast cancer to de-escalate surgical treatments.
Antonio EsguevaChristian SisoMartin Espinosa-BravoCarolina SobridoIgnacio MirandaJuan P SalazarIsabel T RubioPublished in: Journal of surgical oncology (2020)
Achieving a pCR increases BCS and SLN. In selected subgroups, sparing any axillary surgery after NAT maybe feasible. In cN+ patients, any pCR was associated with survival, but not the anatomic site of response.
Keyphrases
- end stage renal disease
- lymph node
- neoadjuvant chemotherapy
- ejection fraction
- chronic kidney disease
- newly diagnosed
- minimally invasive
- sentinel lymph node
- rectal cancer
- prognostic factors
- coronary artery bypass
- patient reported outcomes
- squamous cell carcinoma
- lymph node metastasis
- combination therapy
- real time pcr
- atrial fibrillation
- patient reported