Vascular affection in relation to oxidative DNA damage in metabolic syndrome.
Rokayaa Abd El AzizMary Wadie FawzyNoha KhalilSahar Abdel AttyZainab SabraPublished in: Therapeutic advances in endocrinology and metabolism (2018)
Urinary 8-oxodG is correlated to total cholesterol and LDL in obese patients with metabolic syndrome; signifying its role in the mechanism of dyslipidemia in those patients. Our study highlights the importance of anterior tibial artery diameter measurement and ankle brachial index as an early marker of atherosclerosis, and how it may be an earlier marker than carotid intima-media thickness.
Keyphrases
- metabolic syndrome
- dna damage
- end stage renal disease
- insulin resistance
- newly diagnosed
- ejection fraction
- uric acid
- chronic kidney disease
- oxidative stress
- adipose tissue
- prognostic factors
- peritoneal dialysis
- total knee arthroplasty
- low density lipoprotein
- weight loss
- optical coherence tomography
- skeletal muscle
- optic nerve