PALB2 mutations in BRCA1/2-mutation negative breast and ovarian cancer patients from Poland.

Anna KluskaAneta BalabasMagdalena PiatkowskaKatarzyna CzarnyKatarzyna PaczkowskaDorota NowakowskaMichal MikulaJerzy Ostrowski

Published in: BMC medical genomics (2017)

Germline mutations in the PALB2 gene were observed at a frequency of approximately 1.5% in Polish breast and/or ovarian cancer patients. Our study confirms two recurrent PALB2 mutations; c.172_175delGA and c.509_510delGA.

Keyphrases

copy number
genome wide
transcription factor