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Different kinds of oral contraceptive pills in polycystic ovary syndrome: A systematic review and meta-analysis.

Maria ForslundJohanna MelinSimon AlesiAnnemieke HoekDaniela RomualdiChau Thien TaySelma WitchelAlexia PenaAya MousaHelena Teede
Published in: European journal of endocrinology (2023)
With current evidence, combined regimens containing an antiandrogen (EE/CPA) may be better compared with conventional COCPs in reducing hyperandrogenism, but EE/CPA will not be recommended as a first line COCP treatment by the pending PCOS guideline update, due to higher VTE risk in the general population. Later generation progestins offer theoretical benefits, but better evidence on clinical outcomes is needed in women with PCOS.
Keyphrases
  • polycystic ovary syndrome
  • insulin resistance
  • venous thromboembolism
  • metabolic syndrome
  • adipose tissue
  • skeletal muscle