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A new KIF5B-ERBB4 gene fusion in a lung adenocarcinoma patient.

Edouard GuenziJohan PluvyAlice GuyardMarina NguenangKhedidja RebahZoubida BenrahmouneJérome LamorilAurelie CazesValérie GounantSolenn BrosseauCatherine BoileauGérard ZalcmanNathalie Théou-Anton
Published in: ERJ open research (2021)
ERBB4 fusion is a rare, novel oncogenic event involved in the development of lung adenocarcinoma that is not routinely looked for, although ERBB4 fusion is a potential target for existing pan-ErbB tyrosine kinase and must be implemented in the laboratory https://bit.ly/3nYmGQ9.
Keyphrases
  • tyrosine kinase
  • epidermal growth factor receptor
  • transcription factor
  • genome wide
  • copy number
  • dna methylation
  • risk assessment
  • human health
  • genome wide analysis