Differential response of esophageal cancer cells to particle irradiation.

Sarah HartfielMatthias HäfnerRamon Lopez PerezAlexander RühleThuy TrinhJürgen DebusPeter E HuberNils Henrik Nicolay

Published in: Radiation oncology (London, England) (2019)

Esophageal cancer cells exhibit differential responses to irradiation with photons and 1H, 12C and 16O particles that were independent of tumor histology. Therefore, yet unknown molecular markers beyond histology may help to establish which esophageal cancer patients benefit from the biological effects of particle treatment.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
oxidative stress
signaling pathway
cell death
radiation therapy
cell proliferation
combination therapy