Effects of anti-diabetes medications on cardiovascular and kidney outcomes in Asian patients with type 2 diabetes: a rapid evidence assessment and narrative synthesis.

Takashi KadowakiFumiko YamamotoYusuke TanedaYusuke NaitoDouglas ClarkSøren S LundTomoo OkamuraKohei Kaku

Published in: Expert opinion on drug safety (2021)

Cardiorenal outcomes with glucose-lowering drugs in Asian T2D patients were similar to outcomes in the overall multinational cohorts of these trials. DPP-4 inhibitors appear to demonstrate cardiovascular safety in Asians, while SGLT2 inhibitors and some GLP-1 receptor agonists may reduce cardiorenal and cardiovascular risk, respectively.

Keyphrases

end stage renal disease
type diabetes
cardiovascular disease
newly diagnosed
ejection fraction
prognostic factors
blood pressure
insulin resistance
patient reported outcomes
adipose tissue