Spermatozoa isolation with Felix™ outperforms conventional density gradient centrifugation preparation in selecting cells with low DNA damage.
Pauline VilleneuveFabrice SaezElisa HugAreski ChorfaRachel GuitonBenoit SchubertAndré ForceJoël R DrevetPublished in: Andrology (2023)
The data collected in this study support the preparation of spermatozoa by the Felix™ system as it allows selection of spermatozoa with the highest progressive motility as well as the lowest nuclear/DNA damage. These improved sperm parameters, along with the fact that the Felix™ separation process is very fast and highly standardized, should be of great interest to the assisted reproduction technologies industry.
Keyphrases
- dna damage
- oxidative stress
- induced apoptosis
- dna repair
- molecularly imprinted
- multiple sclerosis
- cell cycle arrest
- big data
- endoplasmic reticulum stress
- biofilm formation
- machine learning
- escherichia coli
- high resolution
- artificial intelligence
- mass spectrometry
- cell proliferation
- pseudomonas aeruginosa
- data analysis
- candida albicans
- simultaneous determination