Alkylation of 6-thiopurine derivatives by the Mitsunobu reaction.
Rafael Dias do Espírito SantoBianca Nascimento Monteiro da SilvaJaime A RabiVagner D PinhoPublished in: Nucleosides, nucleotides & nucleic acids (2023)
Alkylation of thiopurine derivatives with alcohols by the Mitsunobu reaction are reported in moderated to good yields. The method was applied in synthesis of number of thiopurine and thiopurine ribosides derivatives.
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