TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy.
Carolina AlquezarKathleen M SchochEthan G GeierEliana Marisa RamosAurora ScrivoKathy H LiAndrea R ArgouarchElisabeth E MlynarskiBeth A DombroskiMichael A DeTureGourisankar GhoshJennifer S YokoyamaAna Maria CuervoAlma L BurlingameGerard D SchellenbergTimothy M MillerBruce L MillerAimee W KaoPublished in: Science advances (2021)
[Figure: see text].