Changes in Diffuse Optical Tomography Images During Early Stages of Neoadjuvant Chemotherapy Correlate with Tumor Response in Different Breast Cancer Subtypes.
Mirella L AltoeKevin KalinskyAlessandro MaroneHyun K KimHua GuoHanina HibshooshMariella TejadaKatherine D CrewMelissa K AccordinoMeghna S TrivediDawn L HershmanAndreas H HielscherPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
This study demonstrates that DOTBIS measured features change over time according to tumor pCR status and may predict early in the NAC treatment course whether a patient is responding to NAC.
Keyphrases
- neoadjuvant chemotherapy
- transcription factor
- locally advanced
- lymph node
- sentinel lymph node
- deep learning
- case report
- high resolution
- convolutional neural network
- squamous cell carcinoma
- genome wide analysis
- high speed
- optical coherence tomography
- machine learning
- early stage
- mass spectrometry
- electron microscopy