Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study.

Olav SundnesWilliam OttestadCamilla SchjalmPeter LundbäckLars la Cour PoulsenTom Eirik MollnesGuttorm HaraldsenTorsten Eken

Published in: Molecular medicine (Cambridge, Mass.) (2021)

We describe for the first time early high-resolution IL-33 concentration kinetics in individual patients after trauma and correlate systemic IL-33 release to clinical data. These findings provide insight into a potentially important axis of danger signaling in humans.

Keyphrases

high resolution
end stage renal disease
endothelial cells
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
mass spectrometry
trauma patients
early onset
patient reported outcomes
tandem mass spectrometry
loop mediated isothermal amplification
sensitive detection