MALBoost: a web-based application for gene regulatory network analysis in Plasmodium falciparum.
Roelof van WykRiëtte van BiljonLyn-Marie BirkholtzPublished in: Malaria journal (2021)
The MALBoost application provides the first tool for easy interfacing and efficiently allows gene regulatory network construction for Plasmodium. Additionally, access is provided to a pre-compiled network for use as reference framework. Validation for sexually committed ring-stage parasite targets of AP2-G, suggests the algorithm was effective in resolving "traditionally" low-level signatures even in bulk RNA datasets.