Optimal use of tranexamic acid for total hip arthroplasty: A network meta-analysis.
Byung-Ho YoonTae-Young KimYoung Seung KoYoung-Kyun LeeYong-Chan HaKyung-Hoi KooPublished in: PloS one (2018)
A network meta-analysis indicated that combined administration of TXA (IV and topical) was effective in reducing the transfusion rate after hip arthroplasty compared with IV or topical alone. As no high-risk patients were evaluated in the RCTs, it is not known whether the combined method is safer for patients susceptible to DVT or PE.