Optimizing Workflows for Fast and Reliable Metabolic Tumor Volume Measurements in Diffuse Large B Cell Lymphoma.
Coreline N BurggraaffFareen RahmanIsabelle KaßnerSimone PieplenboschSally F BarringtonYvonne W S JauwGerben J C ZwezerijnenStefan MüllerOtto S HoekstraJosée M ZijlstraHenrica C W De VetRonald Boellaardnull nullPublished in: Molecular imaging and biology (2021)
Improved interobserver reliability and ease of use occurred using fully automated preselection (using SUV≥4.0 and volume≥3ml, Workflow B) compared with individual lesion selection by observers (Workflow A). Subsequent manual modification was necessary for some patients but reduced interobserver reliability which may need to be balanced against potential improvement on prognostic accuracy.