Integrated analysis of human transcriptome data for Rett syndrome finds a network of involved genes.

Friederike Ehrhart Susan L M Coort Lars M T Eijssen Elisa CirilloEric E SmeetsNasim Bahram Sangani Chris T A Evelo Leopold M G Curfs

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2019)

Integrative analysis of omics data and prior knowledge databases is a powerful approach to identify links between mutation and phenotype especially in rare disease research where little data is available.

Keyphrases

electronic health record
big data
endothelial cells
single cell
genome wide
healthcare
gene expression
data analysis
network analysis
deep learning
genome wide analysis