Hematopoietic Cell Transplantation for Severe Combined Immunodeficiency Patients: a Japanese Retrospective Study.

Satoshi MiyamotoKatsutsugu UmedaMio KurataAkira NishimuraMasakatsu YanagimachiMasataka IshimuraMaho SatoTomonari ShigemuraMotohiro KatoYoji SasaharaAkihiro IguchiTakashi KoikeYoshiyuki TakahashiMichiko KajiwaraMasami InoueYoshiko HashiiHiromasa YabeKoji KatoYoshiko AtsutaKohsuke ImaiTomohiro Morio

Published in: Journal of clinical immunology (2021)

We showed the potential of HLA-matched UCB as a donor source with higher priority for SCID patients. We also demonstrated that early age at HCT without active infection is critical for a better prognosis, highlighting the importance of newborn screening for SCID.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
early onset