Current Controversies in Metabolic Surgery for Nonalcoholic Fatty Liver Disease.
Iraklis PerysinakisHarilaos C PappisElias MargarisPublished in: Obesity surgery (2020)
Nonalcoholic fatty liver disease (NAFLD) represents the most common liver disease, and it is expected to become the leading cause of end-stage liver disease in the near future. Bariatric operations have beneficial effects on NAFLD, inducing histological resolution of liver damage through weight loss-dependent and weight loss-independent mechanisms. Due to lack of randomized controlled trials, no specific guidelines have been established so far. Yet there is growing evidence that NAFLD will eventually become a formal indication for metabolic surgery. Data regarding the choice of procedure are conflicting, although gastric bypass seems to be slightly superior to sleeve gastrectomy. The purpose of this review is to provide an update on the ongoing research regarding the role of metabolic surgery in NAFLD management.
Keyphrases
- weight loss
- gastric bypass
- minimally invasive
- roux en y gastric bypass
- coronary artery bypass
- bariatric surgery
- obese patients
- surgical site infection
- type diabetes
- metabolic syndrome
- coronary artery disease
- glycemic control
- machine learning
- physical activity
- single molecule
- weight gain
- clinical practice
- adipose tissue
- atrial fibrillation
- percutaneous coronary intervention
- data analysis
- decision making