Diminished cerebral oxygen extraction and metabolic rate in sickle cell disease using T2 relaxation under spin tagging MRI.
Adam M BushThomas D CoatesJohn C WoodPublished in: Magnetic resonance in medicine (2017)
Cerebral and peripheral oxygen extraction are decreased in SCD patients, suggesting either blood flow is increased beyond metabolic demands or the presence of physiological arterial-venous shunting. Magn Reson Med 80:294-303, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
Keyphrases
- blood flow
- sickle cell disease
- magnetic resonance
- end stage renal disease
- subarachnoid hemorrhage
- ejection fraction
- contrast enhanced
- newly diagnosed
- magnetic resonance imaging
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- single molecule
- room temperature
- patient reported outcomes
- patient reported
- molecular dynamics