Outcomes of patients with diffuse large B-cell and high-grade B-cell lymphomas with synchronous CNS and systemic involvement at diagnosis treated with high-dose methotrexate and R-CHOP: a single-center retrospective study.

Megan FlemingYing HuangEmily DotsonDavid A BondJohn ReneauNarendranath EpperlaLapo AlinariJonathan BrammerBeth ChristianRobert A BaiocchiKami MaddocksYazeed Sawalha

Published in: Therapeutic advances in hematology (2022)

CNS involvement in aggressive B-cell non-Hodgkin lymphoma at diagnosis dictates clinical outcomes and requires more effective treatment options.

Keyphrases

high dose
high grade
low grade
blood brain barrier
stem cell transplantation
low dose
diffuse large b cell lymphoma
skeletal muscle
insulin resistance
drug induced