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Effect of pre-operative methylprednisolone on orthostatic hypotension during early mobilization after total hip arthroplasty.

Viktoria Lindberg-LarsenP B PetersenØ JansT BeckH Kehlet
Published in: Acta anaesthesiologica Scandinavica (2018)
Pre-operative administration of 125 mg methylprednisolone IV did not reduce OH or OI compared with placebo despite a reduced inflammatory response.
Keyphrases
  • total hip arthroplasty
  • inflammatory response
  • high dose
  • lipopolysaccharide induced
  • lps induced
  • toll like receptor
  • low dose
  • double blind
  • phase iii
  • clinical trial
  • immune response