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Cellular distribution of PACAP-38 and PACAP receptors in the rat brain: Relation to migraine activated regions.

Karin WarfvingeLars Edvinsson
Published in: Cephalalgia : an international journal of headache (2019)
The findings suggest that the rich supply of PACAP-38 and PAC1 receptors is associated with basic functional responses in the central nervous system (CNS), and there are important close anatomical relations with calcitonin gene-related peptide in CNS regions associated with migraine pathophysiology.
Keyphrases
  • blood brain barrier
  • genome wide
  • copy number
  • gene expression
  • dna methylation
  • transcription factor
  • drug induced