Prospecting Specific Protein Patterns for High Body Mass Index (BMI), Metabolic Syndrome and Type 2 Diabetes in Saliva and Blood Plasma From a Brazilian Population.

Carlos Vinicius Ferreira da SilvaCarlos José Ferreira da SilvaYoussef Bacila SadeSandra Mara Naressi ScapinFabiano L ThompsonCristiane ThompsonCarina Maciel da Silva-BoghossianEidy de Oliveira Santos

Published in: Proteomics. Clinical applications (2024)

Our data revealed similar alterations in protein composition across individuals with abnormal weight gain, T2DM, and MeS. This finding confirms the close link between these conditions at the molecular level in the studied population, potentially enhancing our understanding of these diseases and paving the way for the development of novel diagnostic tools.

Keyphrases

weight gain
body mass index
metabolic syndrome
type diabetes
birth weight
protein protein
insulin resistance
electronic health record
amino acid
physical activity
cardiovascular disease
binding protein
single cell
uric acid
machine learning
small molecule
single molecule
skeletal muscle
data analysis