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Structural alterations and inflammation in the heart after multiple trauma followed by reamed versus non-reamed femoral nailing.

Meike BaurBirte WeberIna LacknerFlorian GebhardRoman PfeiferPaolo CinelliSascha HalvachizadehMichel TeubenMiriam LipiskiNikola CesarovicHans-Christoph PapeMiriam Kalbitz
Published in: PloS one (2020)
Multiple trauma induced cardiac structural alterations in vivo, which might contribute to the development of early myocardial damage (EMD). This study also revealed that reamed femoral nailing (reamed) is associated with more prominent immunological cardiac alterations compared to nailing without reaming (non-reamed). This suggests that the choice of the initial fracture treatment strategy might be crucial for the overall outcome as well as for any post-traumatic cardiac consequences.
Keyphrases
  • left ventricular
  • oxidative stress
  • heart failure
  • atrial fibrillation
  • high glucose
  • single cell
  • decision making