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Glazed clay pottery and lead exposure in Mexico: Current experimental evidence.

Araceli Diaz-RuizLuis Antonio Tristán-LópezKaren Itzel Medrano-GómezJuan Alejandro Torres-DomínguezCamilo RíosSergio Montes
Published in: Nutritional neuroscience (2016)
We found that clay pots, jars, and mugs leached on average 200 µg/l lead, and exposure to the lemonade resulted in 2.5 µg/dl of lead in the pregnant rats' blood. Neonates also showed increased lead content in the hippocampus and cerebellum. Caspase-3 activity was found to be statistically increased in the hippocampus in prenatally exposed neonates, suggesting increased apoptosis in that brain region. Glazed ceramics are still an important source of lead exposure in Mexico, and our results confirm that pregnancy is a vulnerable period for brain development.
Keyphrases
  • cerebral ischemia
  • cell death
  • white matter
  • oxidative stress
  • resting state
  • multiple sclerosis
  • signaling pathway
  • functional connectivity
  • blood brain barrier
  • prefrontal cortex
  • preterm infants