Icosahedral boron clusters as modifying entities for biomolecules.
Tomasz Marek GoszczyńskiKrzysztof FinkJanusz BoratyńskiPublished in: Expert opinion on biological therapy (2019)
Boron clusters are suitable for altering structural and functional features of biomolecules and can be used in the development of new drugs and drug delivery systems. The high affinity of boron clusters, especially metallacarboranes, to albumin creates a new possibility to use them to optimize the pharmacokinetics of biologically active peptides. Boron clusters have high potential in biological and medicinal applications. Due to their peculiar properties, they can be used to optimize parameters critical for the biological activity of therapeutic substances and their affinity toward biological targets.
Keyphrases