Preparation and Characterization of Nanostructured Lipid Carriers (NLCs) Containing Glycyrrhiza glabra Extract for the Treatment of Skin Hyperpigmentation.

Afsaneh Hoseinsalari Hoda Atapour-Mashhad Javad Asili Zahra Tayarani-Najaran Leila Mohtashami Mahnaz Khanavi Mahdi Vazirian Hamid Akbari Javar Somayeh Niknam Shiva Golmohammadzadeh Mohammad Reza Shams Ardekani

Published in: Current pharmaceutical design (2024)

The LG-NLC formulation has revealed desirable surface characterization, good physiochemical stability, efficient drug release pattern and in vivo penetration, and high EE%. Therefore, it can be a suitable nanosystem for the delivery of licorice extract in the treatment of hyperpigmentation.

Keyphrases

drug release
drug delivery
oxidative stress
anti inflammatory
single cell
replacement therapy