Heterogeneity of ovarian matrisome hydrogels elucidates factors that may influence follicle growth in vitro.

Hannah B McDowellNathaniel F HenningMonica M Laronda

Published in: Reproduction (Cambridge, England) (2024)

This work describes a valuable and reproducible method for generating optically clear bovine ovary-derived hydrogels that support in vitro murine follicle growth. These techniques are the foundation in which follicle growth dynamics and matrisome protein composition may be correlated to reveal the influence of matrisome proteins on folliculogenesis.

Keyphrases

drug delivery
single cell
genome wide
extracellular matrix
drug release
small molecule
dna methylation