Defective Allele of the Neuronal Nitric Oxide Synthase Gene Increases Insulin Resistance During Acute Phase of Myocardial Infarction.
Otávio Toledo NóbregaAlessandra M Campos-StafficoElayne Kelen OliveiraDaniel B MunhozFilipe Azevedo MouraLuiz Sérgio Fernandes de CarvalhoAlexandre Anderson De Sousa Munhoz SoaresCiro Martins GomesAudrey Cecília Tonet FuriosoAndrei Carvalho Spositonull nullPublished in: International journal of general medicine (2021)
A defective nNOS allele (and due decline in NO production) seemed to elicit a hyperinsulinemia response to compensate for an insulin-resistant state during the acute phase of STEMI and to be associated with poor endothelial function after the acute phase.
Keyphrases
- nitric oxide synthase
- insulin resistance
- nitric oxide
- type diabetes
- glycemic control
- adipose tissue
- heart failure
- left ventricular
- endothelial cells
- percutaneous coronary intervention
- metabolic syndrome
- copy number
- genome wide
- high fat diet
- st elevation myocardial infarction
- st segment elevation myocardial infarction
- polycystic ovary syndrome
- skeletal muscle
- cerebral ischemia
- genome wide identification
- acute coronary syndrome