A randomized controlled trial of two dialysate sodium concentrations in hospitalized hemodialysis patients.
Finnian R Mc CauslandKatherine Scovner RaviKatherine A CurtisZoé A KibbelaarSamuel A P ShortAnika T SinghSimon CorreaSushrut S WaikarPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2021)
In this RCT for hospitalized maintenance HD patients, we found no difference in the absolute SBP decline between those who received higher versus lower DNa in intention-to-treat analyses. Post-hoc adjusted analyses suggested a lower risk of IDH with higher DNa - thus, larger multi-center studies to confirm these findings are warranted.