Immunogenicity Parameters of Cancer Patients Receiving the mRNA Vaccine BNT162b2 While Obtaining Radiotherapy: A Longitudinal Cohort Evaluation.
Paul ThöneMargot EggerMarija Geroldinger-SimicHarald KindermannLukas KocikNicola KarasekBarbara FischerlehnerKurt SpieglGeorg GruberBernhard AschacherBenjamin DieplingerMartin ClodiWerner LangstegerPublished in: Vaccines (2024)
Pure radiotherapy in cancer patients does not interfere with the vaccine-induced humoral immune response or other immunogenetic aspects, whereas previous or simultaneous chemotherapy does. Findings are of particular relevance for future epidemic or pandemic scenarios.
Keyphrases
- immune response
- locally advanced
- early stage
- rectal cancer
- papillary thyroid
- radiation therapy
- radiation induced
- coronavirus disease
- sars cov
- squamous cell carcinoma
- climate change
- high glucose
- dendritic cells
- diabetic rats
- squamous cell
- toll like receptor
- binding protein
- lymph node metastasis
- endothelial cells
- oxidative stress
- drug induced