Summer Hospitalization and Bronchial Asthma Make Treatment of Respiratory Syncytial Virus Infection Difficult: A Retrospective Study in Japan.
Kosuke OikawaHirotaka OchiaiKazuhiko MatsuhashiMotoichiro SakuraiManabu SuzukiMasaya KoganesawaTomomasa TeradaYoko IshiiAkatsuki KokazeKatsumi MizunoPublished in: Global pediatric health (2022)
In recent years, epidemics of respiratory syncytial virus (RSV) have been seen in the summer in Japan. Patients hospitalized in the summer used a high-flow oxygen administration device more frequently than patients hospitalized in the winter. This study was a retrospective study to examine the variables associated with duration of oxygen therapy and severe cases. Subjects were pediatric patients diagnosed with RSV infection and hospitalized for treatment during the 5 years from April 2014 to March 2019. Data from 292 patients were analyzed. Duration of oxygen therapy was significantly associated with bronchial asthma (partial regression coefficient: 0.897, P = .004). Hospitalization in summer was significantly associated with severe condition (adjusted odds ratio: 4.07, 95% confidence interval: 1.16-14.27). The present study showed that bronchial asthma is a risk factor for prolonged oxygen therapy and infection in summer is a risk factor for progression to severe condition in cases of RSV infection.
Keyphrases
- respiratory syncytial virus
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- chronic obstructive pulmonary disease
- heat stress
- early onset
- stem cells
- magnetic resonance imaging
- patient reported outcomes
- machine learning
- mesenchymal stem cells
- computed tomography
- cystic fibrosis
- artificial intelligence
- respiratory tract
- drug induced
- bone marrow
- combination therapy
- contrast enhanced