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Downregulation of circ-STK39 suppresses pancreatic cancer progression by sponging mir-140-3p and regulating TRAM2-mediated epithelial-mesenchymal transition.

Chao LiJuanjuan CaiWeifeng LiuZhenzhen GaoGuogang Li
Published in: Apoptosis : an international journal on programmed cell death (2023)
In this regard, we showed that circ-STK39 downregulation led to decreased migration, proliferation and the EMT of PC via the miR-140-3p/TRAM2 axis.
Keyphrases
  • signaling pathway
  • epithelial mesenchymal transition
  • transforming growth factor
  • cell proliferation