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A selective c-Met and Trks inhibitor Indo5 suppresses hepatocellular carcinoma growth.

Teng LuoShou-Guo ZhangLing-Fei ZhuFei-Xiang ZhangWei LiKe ZhaoXiao-Xue WenMiao YuYi-Qun ZhanHui ChenChang-Hui GeHui-Ying GaoLin WangXiao-Ming YangChang-Yan Li
Published in: Journal of experimental & clinical cancer research : CR (2019)
These findings indicate that Indo5 is associated with marked suppression of c-Met and Trks co-expressing HCC, supporting its clinical development as an antitumor treatment for HCC patients with co-active c-Met and Trks signaling.
Keyphrases
  • tyrosine kinase
  • combination therapy