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Melanoma-specific survival before and after inclusion in a familial melanoma dermatologic surveillance program in CDKN2A mutation carriers and non-carriers.

Maria PissaJan LapinsChristina SköldmarkHildur Helgadottir
Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2022)
This study is the first to address the impact on survival from introducing a dermatologic surveillance program to familial melanoma cases with or without CDKN2A mutations. The CDKN2A-mut carriers appeared to have a clear benefit with less advanced melanomas diagnosed and better melanoma-specific survival after inclusion. Among the CDKN2A-wt cases, the effect of the inclusion on the studied outcomes was less evident.
Keyphrases
  • skin cancer
  • public health
  • quality improvement
  • early onset
  • basal cell carcinoma
  • free survival
  • adipose tissue
  • insulin resistance
  • skeletal muscle
  • weight loss