Driving pressure, as opposed to tidal volume based on predicted body weight, is associated with mortality: results from a prospective cohort of COVID-19 acute respiratory distress syndrome patients.
Erich Vidal CarvalhoMaycon de Moura ReboredoEdimar Pedrosa GomesPedro Nascimento MartinsGabriel Paz Souza MotaGiovani Bernardo CostaFernando Antônio Basile ColugnatiBruno do Valle PinheiroPublished in: Critical care science (2024)
In patients with acute respiratory distress syndrome caused by COVID-19, exposure to higher driving pressure, as opposed to higher tidal volume/kg predicted body weight, is associated with greater mortality. These results suggest that driving pressure might be a primary target for lung-protective mechanical ventilation in these patients.
Keyphrases
- acute respiratory distress syndrome
- mechanical ventilation
- body weight
- extracorporeal membrane oxygenation
- end stage renal disease
- coronavirus disease
- sars cov
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- type diabetes
- cardiovascular events
- respiratory failure
- carbon dioxide
- patient reported