Effects of Reduced Nicotine Content Cigarettes on Fractional Exhaled Nitric Oxide (FeNO) and Self-Reported Respiratory Health Outcomes among Smokers with Psychiatric Conditions or Socioeconomic Disadvantage.

Should a reduced nicotine content standard be implemented; these results suggest that reduced nicotine content in cigarettes will not exacerbate and instead may attenuate smoking-related decreases in FeNO. This is significant as NO is an important component in maintaining a healthy respiratory system and necessary to defend against infection. Furthermore, the results of the current study demonstrate that the adoption of the reduced nicotine content standard may result in beneficial impacts on respiratory epithelial health among vulnerable populations that are disproportionally affected by the adverse health outcomes precipitated by combustible tobacco use.