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Developmental trajectories of body mass index from childhood into late adolescence and subsequent late adolescence-young adulthood cardiometabolic risk markers.

Kolade OluwagbemigunAnette E BuykenUte AlexyMatthias SchmidChristian HerderUte Nöthlings
Published in: Cardiovascular diabetology (2019)
We identified sex-specific distinct trajectories of BMI SDS from childhood into late adolescence, higher maternal prepregnancy BMI as a common determinant of the 'high-normal weight' and 'overweight' trajectories, and 'overweight' trajectory being associated with elevated IL-18 in late adolescence-young adulthood. This study emphasizes the role of maternal prepregnancy BMI in overweight, and highlights IL-18 as a cardiometabolic signature of overweight across life.
Keyphrases
  • weight gain
  • depressive symptoms
  • body mass index
  • birth weight
  • physical activity
  • weight loss
  • early life
  • middle aged
  • pregnant women
  • pregnancy outcomes
  • young adults
  • gestational age