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Seven cases of hereditary haemorrhagic telangiectasia-like hepatic vascular abnormalities associated with EPHB4 pathogenic variants.

Alexandre GuilhemSophie Dupuis-GirodOlivier EspitiaSophie RivièreJulie SeguierMallorie KerjouanChristian LavigneHélène MaillardPascal MagroLaurent AlricDan LipskerAntoine ParrotVanessa LeguyClaire VanlemmensLaurent GuibaudMiikka VikkulaMelanie EyriesPierre-Jean ValetteSophie Giraud
Published in: Journal of medical genetics (2023)
loss-of-function variants can be associated with HHT-like hepatic abnormalities and should be tested for atypical HHT presentations.
Keyphrases
  • copy number
  • gene expression
  • dna methylation